SITC's fully open-access journal: checkpoint-inhibitor and cell-therapy trials, immune-related toxicity management guidelines and immunotherapy biomarkers.
Fully open access, published by BMJ on behalf of the Society for Immunotherapy of Cancer. Publishes phase 1 and 2 immunotherapy trials, SITC clinical practice guidelines on immune-related adverse events and biomarkers, and the SITC annual meeting abstracts. Strong on real-world toxicity and combination strategies.
This is the paper Europe PMC returns for registry id NCT05877430 with the most citations, so it is the natural first reading for anyone following the trial. Read the abstract above alongside the trial page and the registry entry; the record was linked automatically and its figures have not been checked by hand.
This is the paper Europe PMC returns for registry id NCT03068455 with the most citations, so it is the natural first reading for anyone following the CheckMate 915 trial. Read the abstract above alongside the trial page and the registry entry; the record was linked automatically and its figures have not been checked by hand.
This cohort, with the locally advanced cohort in the label, is the evidence behind cosibelimab's December 2024 US approval. The response rate is of the same order as cemiplimab and pembrolizumab in this cancer, which gives patients a third checkpoint antibody option, though none of the three has been compared head to head.
This is the paper Europe PMC returns for registry id NCT05081609 with the most citations, so it is the natural first reading for anyone following the trial. Read the abstract above alongside the trial page and the registry entry; the record was linked automatically and its figures have not been checked by hand.
One of the most cited trial reports Europe PMC returns for Durvalumab in Endometrial cancer, so it is a natural first reading for anyone weighing the idea it is linked from. The record was linked automatically by title and abstract; read the abstract above and the paper itself before relying on any figure.
One cancer page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
A second publication from the KEYNOTE-017 trial, later than the first and described in its title as an update or longer-term analysis. Read it with the primary publication linked from the trial page; the record was linked automatically and its figures have not been checked by hand.
One bottleneck page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
A second publication from the JAVELIN Merkel 200 trial, later than the first and described in its title as an update or longer-term analysis. Read it with the primary publication linked from the trial page; the record was linked automatically and its figures have not been checked by hand.
Led KEYNOTE-040, which showed pembrolizumab improves survival in previously treated head and neck cancer.
Giampaolo Tortora is a medical oncologist who directs the Gemelli comprehensive cancer centre.
Professor who is Medical Director of Trinity St James's Cancer Institute, Ireland's first academic comprehensive cancer institute, in Dublin.
Gynaecologic oncologist and immunotherapy researcher who directs the University of Chicago Medicine Comprehensive Cancer Center.
Michael von Bergwelt is a haematologist who leads LMU's cell therapy and immuno-oncology programme.
Michelle Xia founded Akeso, the Zhongshan company whose bispecific antibody ivonescimab was the first drug to beat pembrolizumab in a head-to-head trial.
Robert Martuza built the first genetically engineered virus designed to treat a cancer, a herpes virus crippled so that it could only replicate in dividing tumour cells.
President of Seoul St. Mary's Hospital, the flagship 1,374-bed hospital of the Catholic University of Korea, which he is steering towards personalised, patient-centred care in cancer and other major diseases.
This is the paper Europe PMC returns for registry id NCT05877430 with the most citations, so it is the natural first reading for anyone following the trial. Read the abstract above alongside the trial page and the registry entry; the record was linked automatically and its figures have not been checked by hand.
This is the paper Europe PMC returns for registry id NCT03068455 with the most citations, so it is the natural first reading for anyone following the CheckMate 915 trial. Read the abstract above alongside the trial page and the registry entry; the record was linked automatically and its figures have not been checked by hand.
This cohort, with the locally advanced cohort in the label, is the evidence behind cosibelimab's December 2024 US approval. The response rate is of the same order as cemiplimab and pembrolizumab in this cancer, which gives patients a third checkpoint antibody option, though none of the three has been compared head to head.
This is the paper Europe PMC returns for registry id NCT05081609 with the most citations, so it is the natural first reading for anyone following the trial. Read the abstract above alongside the trial page and the registry entry; the record was linked automatically and its figures have not been checked by hand.
One of the most cited trial reports Europe PMC returns for Durvalumab in Endometrial cancer, so it is a natural first reading for anyone weighing the idea it is linked from. The record was linked automatically by title and abstract; read the abstract above and the paper itself before relying on any figure.
One cancer page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
A second publication from the KEYNOTE-017 trial, later than the first and described in its title as an update or longer-term analysis. Read it with the primary publication linked from the trial page; the record was linked automatically and its figures have not been checked by hand.
One bottleneck page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
Shares Three-year survival, correlates and salvage therapies in patients receiving first-line pembrolizumab for advanced Merkel cell carcinoma, Immune-related adverse events (irAEs).
Shares Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial, Immune-related adverse events (irAEs).
Shares Immune checkpoint, Immune-related adverse events (irAEs).