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eLife
A non-profit open-access life-science journal backed by HHMI, Wellcome and the Max Planck Society, known for its reviewed-preprint publishing model.
Also called: eLife
Overview
Fully open access. Since 2023 eLife publishes 'Reviewed Preprints' with public peer reviews and an editorial assessment instead of accept/reject decisions, a model that has been both praised and contested. Publishes cancer biology, evolution and computational studies, including reproducibility work on high-profile cancer papers.
Publisher
eLife Sciences Publications
Scope
basic cancer biology
Website
Access model
open access
Founded
2012
ISSN
2050-084X
meta analysis2021176 citations
Reproducibility Project: Cancer Biology found that landmark preclinical results mostly shrank or vanished on replication
Many exciting laboratory findings that motivate drug programmes are weaker or less reliable than published, which helps explain the high failure rate of drugs entering clinical trials. It argues for pre-registration, detailed methods, data sharing and independent replication before major translational investment.
observational2013467 citations
Evolutionary dynamics of cancer in response to targeted combination therapy
One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
Partha Basu
Head, Early Detection, Prevention and Infections Branch, IARC
Cervical cancer screeningHPVEarly detection in low-resource settings
Leads IARC's early detection and prevention work, central to the WHO cervical cancer elimination strategy.
Richard Van Etten
Director, Chao Family Comprehensive Cancer Center, University of California, Irvine
Haematological malignanciesLeukaemia biologyCancer centre leadership
Physician-scientist who directs the Chao Family Comprehensive Cancer Center at UC Irvine, the NCI-designated comprehensive cancer centre for Orange County.
meta analysiseLife 2021176 citations
Reproducibility Project: Cancer Biology found that landmark preclinical results mostly shrank or vanished on replication
Many exciting laboratory findings that motivate drug programmes are weaker or less reliable than published, which helps explain the high failure rate of drugs entering clinical trials. It argues for pre-registration, detailed methods, data sharing and independent replication before major translational investment.
observationaleLife 2013467 citations
Evolutionary dynamics of cancer in response to targeted combination therapy
One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.