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For the biggest claims, journals would require that a second, independent laboratory repeated the central experiment before the paper is accepted.
Some fields (particle physics with independent detectors, genome-wide association studies with replication cohorts) require independent confirmation as a condition of publication. Cancer biology does not. Top journals could require, for papers whose central claim is a therapeutic effect in a model system, that an independent lab (declared, without shared authorship interests) reproduce the key experiment, with the replication reported in the paper.
Shares Independent replication of the key experiment before first-in-human academic trials, Preclinical results do not reproduce.
Shares Multi-laboratory preclinical trials as the standard for go/no-go decisions, Preclinical results do not reproduce.
Shares Independent replication of the key experiment before first-in-human academic trials, Preclinical results do not reproduce.