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Results can change when a supplier changes a batch of serum, antibody or growth factor. Recording which batch was used in each experiment, in a shared ledger, would let these effects be spotted.
Lot-to-lot variation in serum, media supplements, antibodies and enzymes is a recognised but untracked source of irreproducibility. A shared, machine-readable ledger of reagent lots (vendor, catalogue and lot number, hashed) linked to experiments and publications, populated by lab inventory software and vendor APIs, would let batch effects be detected across the community and would let vendors be held accountable for problem lots.
Shares Only use antibodies proven to hit their target with knockout controls, Preclinical results do not reproduce.
Shares A digital passport for every cell culture: identity, contamination status, passage number, Preclinical results do not reproduce.
Shares A digital passport for every cell culture: identity, contamination status, passage number, Preclinical results do not reproduce.