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Patients report symptoms on their phone each week; a set of rules turns severe or worsening symptoms into a dose hold or reduction before the next clinic visit. This could keep people on treatment longer and feeling better.
Protocolised dose-modification algorithms triggered by weekly PRO-CTCAE reports (with nurse review), compared in a randomised trial with standard clinician-assessed dose modification at scheduled visits. Builds on the randomised evidence that symptom monitoring with alerts improved QoL and survival in chemotherapy patients, extending it to dosing decisions for oral agents.
Shares Wrong doses, Toxicity and quality of life are undervalued, Small-molecule kinase inhibitors.
Shares Wrong doses, Toxicity and quality of life are undervalued, Small-molecule kinase inhibitors.
Shares Wrong doses, Toxicity and quality of life are undervalued, Small-molecule kinase inhibitors.
Shares Wrong doses, Toxicity and quality of life are undervalued, Small-molecule kinase inhibitors.
Shares Wrong doses, Toxicity and quality of life are undervalued.
Shares Patients lack understanding, navigation and agency, Toxicity and quality of life are undervalued.
Shares Patients lack understanding, navigation and agency, Toxicity and quality of life are undervalued.