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A cheap, old antipsychotic at a low dose is one of the best anti-sickness drugs for chemotherapy. Make sure every cancer unit in the world uses it.
Olanzapine 5 to 10 mg reduces chemotherapy-induced nausea and vomiting in randomised trials, including with highly emetogenic regimens, at a cost of pennies. Uptake is uneven, and in many low-income settings even standard 5-HT3 antagonists and dexamethasone are inconsistently available. The proposal is a global implementation programme: inclusion of olanzapine-based bundles in national essential medicines lists and guidelines, pre-printed order sets, and audit of complete response rates as a quality indicator.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, No incentive to repurpose cheap drugs, Most of the world has almost no cancer care.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, No incentive to repurpose cheap drugs, Most of the world has almost no cancer care.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, No incentive to repurpose cheap drugs, Most of the world has almost no cancer care.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, Most of the world has almost no cancer care.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, Toxicity and quality of life are undervalued.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, Toxicity and quality of life are undervalued.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, Toxicity and quality of life are undervalued.
Shares Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs, Toxicity and quality of life are undervalued.