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LCB84 is an experimental monoclonal antibody from LigaChem Biosciences in phase 2 trials, aimed at TROP2.
LCB84 is a monoclonal antibody developed by LigaChem Biosciences. Its target is TROP2. ClinicalTrials.gov describes the intervention as: TROP2-directed human monoclonal antibody (Ab) linked to a monomethyl auristatin E (MMAE) prodrug. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial. The largest, NCT05941507, plans to enrol 300 participants with primary completion expected 2027-01. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
Monoclonal antibody directed at TROP2, as stated in the ClinicalTrials.gov intervention record; the detailed mechanism is not stated. Connects to TROP2.
1.LCB84 binds TROP2.
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Query for this drug: (TITLE:"LCB84" OR ABSTRACT:"LCB84") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about LCB84, not a curated reading list.
Shares LigaChem Biosciences and the tag pipeline.
Shares LigaChem Biosciences and the tag pipeline.
Shares TROP2 and the tag pipeline.
Shares TROP2 and the tag pipeline.
Shares TROP2 and the tag pipeline.