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HMBD-001 is an experimental monoclonal antibody from Hummingbird Bioscience in phase 2 trials for non-small-cell lung cancer, head and neck squamous cell carcinoma and oesophageal cancer, aimed at HER3 and EGFR.
HMBD-001 is a monoclonal antibody developed by Hummingbird Bioscience. Its targets are HER3 and EGFR. ClinicalTrials.gov describes the intervention as: HMBD-001 is a humanized Immunoglobulin G1 (IgG1) anti-Human Epidermal Growth Factor Receptor 3(HER3) monoclonal antibody (mAb). It is administered intravenously (IV) weekly. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, in non-small-cell lung cancer, head and neck squamous cell carcinoma, oesophageal cancer, cervical cancer and cutaneous squamous cell carcinoma. The largest, NCT05910827, plans to enrol 398 participants with primary completion expected 2027-12-01. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
1.HMBD-001 binds HER3.
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Query for this drug: (TITLE:"HMBD-001" OR ABSTRACT:"HMBD-001") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about HMBD-001, not a curated reading list.
Shares Cutaneous squamous cell carcinoma, Oesophageal cancer, Cervical cancer, Head and neck squamous cell carcinoma and the tag pipeline.
Shares Advanced cutaneous squamous cell carcinoma, Cutaneous squamous cell carcinoma, Head and neck squamous cell carcinoma and the tag pipeline.
Shares Recurrent and metastatic nasopharyngeal carcinoma, Nasopharyngeal carcinoma and the tag pipeline.
Shares Recurrent and metastatic nasopharyngeal carcinoma, Nasopharyngeal carcinoma and the tag pipeline.
Shares Oesophageal cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Oesophageal cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Oesophageal cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Recurrent and metastatic nasopharyngeal carcinoma, Nasopharyngeal carcinoma, Non-small-cell lung cancer and the tag pipeline.