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CAM2029 is Camurus's monthly octreotide depot that patients can inject themselves, positive in the phase 3 SORENTO trial for gastroenteropancreatic neuroendocrine tumours against the standard depot formulations.
Camurus of Lund built CAM2029 on its FluidCrystal lipid depot so that octreotide can be given as a small subcutaneous self-injection rather than the intramuscular Sandostatin LAR. The phase 3 SORENTO trial in advanced gastroenteropancreatic neuroendocrine tumours met its primary endpoint of progression-free survival against octreotide LAR or lanreotide, and the company has filed in Europe and the United States; it is approved for acromegaly as Oczyesa in some markets.
Ball-and-stick model from PubChem 2D record (no 3D conformer available). PubChem record
Octreotide, a somatostatin analogue, released for a month from a lipid depot that forms under the skin after a small ready-to-use injection. Connects to Somatostatin receptor 2.
1.CAM2029 (octreotide subcutaneous depot) binds Somatostatin receptor 2.
Background: ADC sequencing, Antigen escape (antigen loss, lineage switch), BCG-unresponsive, Castration-resistant prostate cancer (CRPC), Circulating tumour DNA (ctDNA). Also on OnCo: Resistance: how tumours escape each drug class · Lines of therapy.
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Query for this drug: (TITLE:"CAM2029" OR ABSTRACT:"CAM2029" OR TITLE:"octreotide subcutaneous depot" OR ABSTRACT:"octreotide subcutaneous depot") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CAM2029 (octreotide subcutaneous depot), not a curated reading list.
Shares Small intestinal neuroendocrine tumours, Neuroendocrine tumours and the tag pipeline.
Shares Small intestinal neuroendocrine tumours, Neuroendocrine tumours and the tag pipeline.
Shares Small intestinal neuroendocrine tumours, Neuroendocrine tumours and the tag pipeline.
Shares Endocrine therapy (SERMs, AIs, SERDs) and the tag pipeline.
Shares Endocrine therapy (SERMs, AIs, SERDs) and the tag pipeline.
Shares Neuroendocrine tumours and the tag pipeline.
Shares Neuroendocrine tumours and the tag pipeline.
Shares Neuroendocrine tumours and the tag pipeline.