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SOPHiA GENETICS
Cloud platform (SOPHiA DDM) that hospitals use to analyse and interpret NGS oncology panels.
Overview
SOPHiA GENETICS, based in Rolle, Switzerland, and listed as SOPH, provides the SOPHiA DDM cloud platform that hospitals use to analyse and interpret next-generation sequencing oncology panels. Its decentralised model lets laboratories sequence locally and interpret in the cloud, and it runs multimodal research programmes combining imaging with genomics. OnCo links it to clinical NGS bioinformatics and variant interpretation. Whether decentralised sequencing with centralised interpretation gives results as consistent as sending samples to one large laboratory is the open question. The bioinformatics technology page carries the wider picture.
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Software in use
The software of oncology →Commercial and regulated products that this organisation sells. Each card says what is behind it: a regulator's database, the literature, a public body's list, or only the company's own words. Listing is not endorsement, and a clearance is a regulatory fact, not a clinical one.
A cloud analysis and interpretation platform hospitals send their sequencing data to, with its own algorithms for variant calling and for scores such as homologous recombination deficiency.
SOPHiA GENETICSPaper 2024