Indapta Therapeutics, of Houston, makes IDP-023, an off-the-shelf natural killer cell therapy from donor g-NK cells, a subset that lacks the FcR gamma chain, and tests it alongside antibody drugs in myeloma and non-Hodgkin lymphoma and in progressive multiple sclerosis. The FDA granted Fast Track status in 2024, and efficacy data are still early.
Indapta Therapeutics is developing IDP-023, a proprietary, off-the-shelf allogeneic FcR gamma-deficient natural killer (g-NK) cell therapy for cancer and autoimmune disease. According to release titles on the company site, the first patients were treated with IDP-023 in January 2024, the FDA granted Fast Track designation for non-Hodgkin lymphoma and myeloma in February 2024, the company received a $4.5 million CPRIT award in May 2024, an IND for progressive multiple sclerosis was cleared in August 2024, a clinical study collaboration with Sanofi in multiple myeloma was announced in December 2024, and clinical activity in relapsed or refractory multiple myeloma was presented in November 2025. SEC Form D filings list the company in Houston, Texas, with about $33.6 million of equity sold in early 2022 and about $50.8 million sold in an offering that began in September 2025.
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Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy, Diffuse large B-cell lymphoma.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy, Diffuse large B-cell lymphoma.
Shares Allogeneic (off-the-shelf) cell therapy, Multiple myeloma, Diffuse large B-cell lymphoma.
Shares Allogeneic (off-the-shelf) cell therapy, Diffuse large B-cell lymphoma.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy, Diffuse large B-cell lymphoma.