Chipscreen discovered chidamide (tucidinostat), the first original epigenetic cancer drug from China, approved in 2014 and later in Japan.
Chidamide (Epidaza) approved 2014 for T-cell lymphoma and 2019 for breast cancer; licensed to HUYA Bioscience (HBI-8000) with Japanese approval 2021 and to Meiji Seika; chiglitazar for diabetes. Founded by Xianping Lu, a returnee from US biotech, before China's regulatory reforms made originator research routine.
Chidamide, approved in 2014, was the first epigenetic cancer drug invented in China and the first oral drug of its kind anywhere, used for T-cell lymphoma and, with hormone therapy, for breast cancer.
Chiauranib is an experimental small-molecule drug from Chipscreen Biosciences in phase 3 trials for ovarian cancer, aimed at VEGF / VEGFR and KIT.
Shares A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients and the tag china.