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Pancreatic Cancer Action Network (PanCAN)
PanCAN is the leading pancreatic cancer patient organisation; it pioneered free tumour molecular profiling for patients (Know Your Tumor) and runs an adaptive platform trial for a disease with few options.
Also called: PanCANsrc-pancan
Overview
Founded 1999. Know Your Tumor showed that ~25% of pancreatic cancers have actionable alterations and that matched therapy improved survival (Pishvaian, Lancet Oncol 2020), influencing NCCN's recommendation for germline and somatic testing in all patients. Precision Promise is a Bayesian adaptive phase 2/3 platform (first readouts 2024). PanCAN's Patient Services provide free case management, clinical trial finder and dietitian access; its advocacy helped double federal pancreatic cancer research funding.
URL
Holds
Pancreatic cancer news, Patient Services case management, Know Your Tumor molecular profiling programme, Precision Promise adaptive platform trial, research grants and the annual 'State of the Science' reports.
Licence
Copyright PanCAN
Maintainer
PanCAN
observationalJAMA Network Open 20211,074 citations
Estimated Projection of US Cancer Incidence and Death to 2040
Pancreatic cancer's share of cancer deaths rises because it is standing still while others improve; the 2014 projection to 2030 already made it the second cause of cancer death in the UK's peer countries, and this is the funding argument charities on both sides of the Atlantic use.
observationalThe Lancet Oncology 2020427 citations
Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial
One collection page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
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