# Pancreatic Cancer Action Network (PanCAN)

Source: https://onco.cc/collections/pancan/  
OnCo record `pancan` (Collection). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

PanCAN is the leading pancreatic cancer patient organisation; it pioneered free tumour molecular profiling for patients (Know Your Tumor) and runs an adaptive platform trial for a disease with few options.

## Summary

Founded 1999. Know Your Tumor showed that ~25% of pancreatic cancers have actionable alterations and that matched therapy improved survival (Pishvaian, Lancet Oncol 2020), influencing NCCN's recommendation for germline and somatic testing in all patients. Precision Promise is a Bayesian adaptive phase 2/3 platform (first readouts 2024). PanCAN's Patient Services provide free case management, clinical trial finder and dietitian access; its advocacy helped double federal pancreatic cancer research funding.

## Fields

- Kind: Collection
- Last checked: 2026-09-08
- Also known as: PanCAN; src-pancan
- Tags: gap-fill; patient-org; source; patient
- URL: https://pancan.org/
- Holds: Pancreatic cancer news, Patient Services case management, Know Your Tumor molecular profiling programme, Precision Promise adaptive platform trial, research grants and the annual 'State of the Science' reports.
- Licence: Copyright PanCAN

## Sources

- PanCAN: https://pancan.org/
- Know Your Tumor outcomes (Lancet Oncol 2020): https://doi.org/10.1016/S1470-2045(20)30074-7
- PanCAN news: https://pancan.org/news/

## Connected records

- cancers: [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/)
- technologies: [Comprehensive genomic profiling](https://onco.cc/technologies/cgp/), [Germline (hereditary) testing](https://onco.cc/technologies/germline-testing/)
- terms: [Basket, umbrella, and platform trials](https://onco.cc/terms/basket-umbrella-platform/), [Tumour-agnostic (tissue-agnostic) approval](https://onco.cc/terms/tumour-agnostic/)
- key papers: [Estimated Projection of US Cancer Incidence and Death to 2040](https://onco.cc/key-papers/paper-rahib-projection-us-cancer-2040-jama-netw-open-2021/), [Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial](https://onco.cc/key-papers/paper-pishvaian-lancet-oncol/)
- roadmaps: [Pancreatic cancer roadmap: from Whipple's operation to gemcitabine, FOLFIRINOX, adjuvant chemotherapy, PARP inhibition, KRAS inhibition, vaccines and the surveillance question](https://onco.cc/roadmaps/pancreatic-roadmap/)
- institutions: [Lustgarten Foundation](https://onco.cc/institutions/lustgarten-foundation/)
- trials: [Precision Promise](https://onco.cc/trials/precision-promise/)
- collections: [PanCAN Know Your Tumor](https://onco.cc/collections/pancan-know-your-tumor/)

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JSON: https://onco.cc/api/v1/entities/pancan.json