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Cancers
Intraductal papillary mucinous neoplasm and other pancreatic cystic precursors
Data

Cancers·Intraductal papillary mucinous neoplasm and other pancreatic cystic precursors

DataIntraductal papillary mucinous neoplasm and other pancreatic cystic precursors

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Overview Types and stages Symptoms and diagnosis Treatment Trials and papers Biology and targets Countries and centres Decisions and support Pipeline and open problems Data

Data

Related pages

62

Direct links plus the targets, companies, and technologies of this cancer's products.

Similar pages

Cancer
Pancreatoblastoma
Shares Solid pseudopapillary neoplasm of the pancreas, Whipple procedure (pancreaticoduodenectomy), Grade, Pancreatic acinar cell carcinoma and the tags subtype-page, gastrointestinal.
Cancer
BRCA or PALB2-mutant pancreatic ductal adenocarcinoma
Shares Diane M. Simeone, Familial pancreatic cancer and inherited risk (who qualifies for surveillance), PRODIGE 24 / CCTG PA6, High-risk pancreatic surveillance (CAPS / PRECEDE) and the tags subtype-page, gastrointestinal.
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Borderline resectable pancreatic ductal adenocarcinoma
Shares Richard Schulick, Pancreas protocol CT (pancreatic protocol CT, dual-phase thin-slice CT with structured reporting), Marc G. Besselink, Resectable, borderline resectable and unresectable and the tags subtype-page, gastrointestinal.
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KRAS G12C-mutant pancreatic ductal adenocarcinoma
Shares CA 19-9, Pancreatic cancer (KEGG map), Mismatch repair deficient (MSI-high) pancreatic ductal adenocarcinoma, KRAS wild-type pancreatic ductal adenocarcinoma and the tags subtype-page, gastrointestinal.
Cancer
Localised small bowel adenocarcinoma (stage I to III, resected)
Shares Endoscopy (EGD, EUS, ERCP), Whipple procedure (pancreaticoduodenectomy), CT (computed tomography), MRI and the tags subtype-page, gastrointestinal.
Cancer
Locally advanced unresectable pancreatic ductal adenocarcinoma
Shares Obstructive jaundice and biliary obstruction, Resectable, borderline resectable and unresectable, CA 19-9, Whipple procedure (pancreaticoduodenectomy) and the tags subtype-page, gastrointestinal.
Cancer
Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell)
Shares CT (computed tomography), MRI, TP53, KRAS and the tags subtype-page, gastrointestinal.
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Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei
Shares CT (computed tomography), MRI, KRAS and the tags subtype-page, gastrointestinal.

technologies

Cell-free DNA methylation tests Comprehensive genomic profiling CT (computed tomography)Cytotoxic chemotherapy DNA methylation profiling Endoscopic ultrasound and EBUS systems High-risk pancreatic surveillance (CAPS / PRECEDE)Liquid biopsy (ctDNA)MRI Multi-cancer early detection (MCED)Platinum agents Robotic & minimally invasive surgery Topoisomerase-I inhibitors (and ADC payloads)

targets

drugs

ApprovedCytotoxic regimen

FOLFIRINOX / mFOLFIRINOX

Phase 3Multi-cancer early detection blood test

companies

pathways

p53 / RB / cell-cycle checkpoint Pancreatic cancer (KEGG map)Wnt / β-catenin

terms

CA 19-9 Endoscopy (EGD, EUS, ERCP)Familial pancreatic cancer and inherited risk (who qualifies for surveillance)Grade High-risk stigmata and worrisome features of pancreatic cysts (IPMN and MCN surgical criteria)New-onset diabetes as a signal of pancreatic cancer (and the ENDPAC score)Obstructive jaundice and biliary obstruction Pancreas protocol CT (pancreatic protocol CT, dual-phase thin-slice CT with structured reporting)Pancreatic intraepithelial neoplasia (PanIN), the microscopic precursor of pancreatic cancer Resectable, borderline resectable and unresectable Whipple procedure (pancreaticoduodenectomy)

trials

EUROPAC PRECEDE PRODIGE 24 / CCTG PA6

roadmaps

Early detection roadmap: organ screening → blood tests for many cancers

ideas

AI that spots pancreatic cancer on scans taken a year before diagnosis Blood-based pancreatic cancer detection in new-onset diabetes Glucose monitor data as an early pancreatic cancer signal New diabetes after 50 plus weight loss triggers a pancreatic cancer check Stop watching stable low-risk pancreatic cysts after five years

people

Anirban Maitra Bert Vogelstein Diane M. Simeone Marc G. Besselink Richard Schulick

key papers

A combination of molecular markers and clinical features improve the classification of pancreatic cysts A revised classification system and recommendations from the Baltimore consensus meeting for neoplastic precursor lesions in the pancreas European evidence-based guidelines on pancreatic cystic neoplasms (2018)Genomic characterization of malignant progression in neoplastic pancreatic cysts International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas (2024)IPMNs with co-occurring invasive cancers: neighbours but not always relatives Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium Pancreatic cancer early detection biomarkers for high-risk individuals: insights from the PRECEDE consortium Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions Pathways of progression from intraductal papillary mucinous neoplasm to pancreatic ductal adenocarcinoma based on molecular features Precancerous neoplastic cells can move through the pancreatic ductal system Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development Revised international consensus Fukuoka guidelines for the management of IPMN of the pancreas (2017)Risk of Neoplastic Progression in Individuals at High Risk for Pancreatic Cancer Undergoing Long-term Surveillance Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

Machine-readable versions

The same record for scripts and assistants; checked 2026-09-18. Data CC BY-NC 4.0, attribute “Data from OnCo (onco.cc)”.

JSON with neighbours Markdown context RDF Turtle Sections with routes and counts API root

ProvenanceLast edited 2026-09-22 · Jude Gomila · Every pancreatic subtype page now rests on two to four la… · diff · file

Wikipedia

Intraductal papillary mucinous neoplasm

Sources & links

Wikipedia
Kyoto guidelines for IPMN (Pancreatology 2024)

subtype-page gastrointestinal

Data

JSON ·

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