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Trials
Evaluation of the Safety and Efficacy of Mifamurtide Versus Standard Treatment With Sorafenib in Patients With High-risk Osteosarcoma

trialsTrialRecruiting

Evaluation of the Safety and Efficacy of Mifamurtide Versus Standard Treatment With Sorafenib in Patients With High-risk Osteosarcoma

A phase 2 trial of Mifamurtide and Sorafenib in Osteosarcoma, run by Anna Raciborska, now recruiting.

Also called: DRAGONFLY

Overview Connected3

Overview

Evaluation of the Safety and Efficacy of Mifamurtide Versus Standard Treatment With Sorafenib in Patients With High-risk Osteosarcoma is a phase 2 interventional study registered as NCT07787429 by Anna Raciborska, with 40 participants planned, started 2026-04-01 and due to reach its primary completion in 2033-07-31. Interventions recorded: Mifamurtide, Sorafenib. Conditions recorded: Osteosarcoma.

Linked to the drug Mifamurtide because the registry names it among its interventions and Osteosarcoma among its conditions. Registry record only: no result has been read by an editor.

Setting

Evaluation of the Safety and Efficacy of Mifamurtide Versus Standard Treatment With Sorafenib in Patients With High-risk Osteosarcoma (DRAGONFLY)

Phase

Phase 2

Sponsor

Anna Raciborska

Registry

Started

2026-04-01

Enrolled

40 enrolled

Connected

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cancers

drugs

ApprovedLiposomal muramyl tripeptide (macrophage activator)

Mifamurtide · Mepact

ApprovedSmall-molecule multi-kinase inhibitor (VEGFR, PDGFR, RAF)

Sorafenib · Nexavar

Evidence strength28/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
40 enrolled+8
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 5 drugs · diff · file

Sources & links

ClinicalTrials.gov NCT07787429

Data

JSON ·

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Cancers

Osteosarcoma

Products

Mifamurtide
Sorafenib

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