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Trials
Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

trialsTrialRecruiting

Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

A phase 1/2 trial of Vactosertib in osteosarcoma, run by MedPacto, Inc., now recruiting.

Overview Connected3

Overview

Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma is a phase 1/2 interventional study registered as NCT05588648 by MedPacto, Inc., with 48 participants planned, started 2023-05-01 and due to reach its primary completion in 2025-09. Interventions recorded: Vactosertib.

Setting

A Phase I/II, Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Vactosertib as a Single Agent in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

Phase

Phase 1/2

Sponsor

MedPacto, Inc.

Registry

Started

2023-05-01

Enrolled

48 enrolled

Connected

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cancers

drugs

Phase 2Oral serine/threonine kinase inhibitor

companies

Evidence strength16/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
48 enrolled+8
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-17 · Jude Gomila · Reverse links for orphaned drugs and companies · diff · file

Sources & links

ClinicalTrials.gov NCT05588648

Data

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Cancers

Osteosarcoma

Products

Vactosertib

Companies

MedPacto

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct05588648.

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