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Trials
First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors

trialsTrialRecruiting

First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors

A phase 1/2 trial of VBC108 in advanced solid tumours, run by VelaVigo Bio Inc, now recruiting.

Overview Connected2

Overview

First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors is a phase 1/2 interventional study registered as NCT07700160 by VelaVigo Bio Inc, with 230 participants planned, started 2026-07-30 and due to reach its primary completion in 2029-07-07. Interventions recorded: VBC108.

Setting

Phase 1/2a Open-label Clinical Trial Evaluating VBC108, a CLDN18.2 and CDH17-directed Bi-specific Antibody Drug Conjugate, in Participants With Advanced Malignant Solid Tumors

Phase

Phase 1/2

Sponsor

VelaVigo Bio Inc

Registry

Started

2026-07-30

Enrolled

230 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
230 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Orphan trials · diff · file

Sources & links

ClinicalTrials.gov NCT07700160

Data

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