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Trials
First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies

trialsTrialRecruiting

First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies

A phase 1/2 trial of VBC101 in advanced solid tumours, run by VelaVigo Bio Inc, now recruiting.

Overview Connected3

Overview

First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies is a phase 1/2 interventional study registered as NCT07136779 by VelaVigo Bio Inc, with 310 participants planned, started 2025-09-23 and due to reach its primary completion in 2027-07-01. Interventions recorded: VBC101.

Setting

PHASE 1/2A OPEN-LABEL CLINICAL TRIAL EVALUATING VBC101, AN EGFR AND CMET TARGETED BI-SPECIFIC ANTIBODY DRUG CONJUGATE, IN PARTICIPANTS WITH ADVANCED SOLID TUMOR MALIGNANCIES

Phase

Phase 1/2

Sponsor

VelaVigo Bio Inc

Registry

Started

2025-09-23

Enrolled

310 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

targets

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
310 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Merge worktree-agent-a5382dd3e7ef16308 (backlinks round) · diff · file

Sources & links

ClinicalTrials.gov NCT07136779

Data

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Cancers

Metastatic cancer (cancer that has spread)

Targets

EGFR

Companies

VelaVigo

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