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Trials
Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors

trialsTrialRecruiting

Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors

A phase 1/2 trial of BNT3214 in advanced solid tumours, run by BioNTech SE, now recruiting.

Overview Connected2

Overview

Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07455734 by BioNTech SE, with 533 participants planned, started 2026-03-30 and due to reach its primary completion in 2030-10. Interventions recorded: BNT3214.

Setting

A Phase I/IIa, First-in-human, Open-label, Multi-site, Multi-regional, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

BioNTech SE

Registry

Started

2026-03-30

Enrolled

533 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
533 enrolled+14
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07455734

Data

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