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Trials
Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

trialsTrialRecruiting

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

A phase 1/2 trial of BNT317 DL1 in advanced solid tumours, run by BioNTech SE, now recruiting.

Overview Connected2

Overview

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06750185 by BioNTech SE, with 248 participants planned, started 2025-01-13 and due to reach its primary completion in 2031-04. Interventions recorded: BNT317 DL1, BNT317 DL2, BNT317 DL3, BNT317 DL4, BNT317 DL5 and BNT317 DL6.

Setting

A Phase I/II, First-in-human, Open-label Trial of the Safety, Efficacy, Tolerability, Pharmacokinetics, and Immunogenicity of BNT317 in Participants With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

BioNTech SE

Registry

Started

2025-01-13

Enrolled

248 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
248 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06750185

Data

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