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Trials
A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.

trialsTrialRecruiting

A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.

A phase 1/2 trial of Bevacizumab, Oxaliplatin and Capecitabine in colorectal cancer, run by Hansoh BioMedical R&D Company, now recruiting.

Overview Connected5

Overview

A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients. is a phase 1/2 interventional study registered as NCT07283367 by Hansoh BioMedical R&D Company, with 502 participants planned, started 2025-12-22 and due to reach its primary completion in 2029-12-31. Interventions recorded: Cohort 1: HS-20110+ Bevacizumab+5-FU/leucovorin, Cohort 2: HS-20110+Bevacizumab+Oxaliplatin+5-FU/leucovorin and Cohort 3: HS-20110+Bevacizumab+Oxaliplatin+Capecitabine.

Setting

A Phase Ib/II Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of HS-20110 Combination Therapies in Patients With Advanced Colorectal Cancer.

Phase

Phase 1/2

Sponsor

Hansoh BioMedical R&D Company

Registry

Started

2025-12-22

Enrolled

502 enrolled

Connected

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cancers

Colorectal cancer

drugs

ApprovedMonoclonal antibody (anti-VEGF)

Bevacizumab · Avastin (and biosimilars)

ApprovedOral fluoropyrimidine prodrug (antimetabolite)

Capecitabine · Xeloda

ApprovedThird-generation platinum (DACH-platinum)

Oxaliplatin · Eloxatin

companies

Hansoh Pharmaceutical

Evidence strength27/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
502 enrolled+14
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Orphan trials · diff · file

Sources & links

ClinicalTrials.gov NCT07283367

Data

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Cancers

Colorectal cancer

Products

Bevacizumab
Oxaliplatin
Capecitabine

Companies

Hansoh Pharmaceutical

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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