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Trials
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

trialsTrialRecruiting

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

A phase 2 trial of BNT324 and PM8002 in advanced solid tumours, run by DualityBio Inc., now recruiting.

Overview Connected5

Overview

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors is a phase 2 interventional study registered as NCT06953089 by DualityBio Inc., with 450 participants planned, started 2025-07-18 and due to reach its primary completion in 2030-06-30. Interventions recorded: DB-1311/BNT324, BNT327 and DB-1305/BNT325.

Setting

A Phase II, Multicenter, Open-Label Trial of DB-1311 in Combination With BNT327 or DB-1305 in Participants With Advanced/Metastatic Solid Tumors

Phase

Phase 2

Sponsor

DualityBio Inc.

Registry

Started

2025-07-18

Enrolled

450 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 3ADC

Phase 3bispecific antibody

companies

BioNTech Duality Biotherapeutics

Evidence strength28/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
450 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06953089

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

BNT324
PM8002

Companies

Duality Biotherapeutics
BioNTech

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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