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Trials
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

trialsTrialRecruiting

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

A phase 1/2 trial of BAY 3713372 in advanced solid tumours, run by Bayer, now recruiting.

Overview Connected2

Overview

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors is a phase 1/2 interventional study registered as NCT06914128 by Bayer, with 450 participants planned, started 2025-03-21 and due to reach its primary completion in 2029-06-18. Interventions recorded: BAY 3713372.

Setting

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics, Pharmacodynamics and Preliminary Clinical Activity of BAY 3713372, a Novel 2nd Generation PRMT5 Inhibitor, in Participants With MTAP-deleted Solid Tumors.

Phase

Phase 1/2

Sponsor

Bayer

Registry

Started

2025-03-21

Enrolled

450 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength21/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
450 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06914128

Data

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