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Trials
DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

trialsTrialRecruiting

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

A phase 2 trial of Temozolomide in glioma & glioblastoma, run by Diakonos Oncology Corporation, now recruiting.

Overview Connected4

Overview

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) is a phase 2 interventional study registered as NCT06805305 by Diakonos Oncology Corporation, with 180 participants planned, started 2025-03-17 and due to reach its primary completion in 2030-03. Interventions recorded: DOC1021, Tumor resection, Temodar (Temozolomide) and SOC cranial radiation.

Setting

Randomized Study of DOC1021 Dendritic Cell Immunotherapy in Combination With Standard of Care for Newly Diagnosed Adult Glioblastoma

Phase

Phase 2

Sponsor

Diakonos Oncology Corporation

Registry

Started

2025-03-17

Enrolled

180 enrolled

Connected

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cancers

Glioma & glioblastoma

drugs

Phase 2Cancer vaccine

ApprovedOral alkylating chemotherapy

Temozolomide · Temodar

companies

Diakonos Oncology

Evidence strength31/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
180 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-17 · Jude Gomila · Reverse links for orphaned drugs and companies · diff · file

Sources & links

ClinicalTrials.gov NCT06805305

Data

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Cancers

Glioma & glioblastoma

Products

Temozolomide
DOC1021

Companies

Diakonos Oncology

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