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Trials
SNV4818 in Participants With Advanced Solid Tumors

trialsTrialRecruiting

SNV4818 in Participants With Advanced Solid Tumors

A phase 1/2 trial of Fulvestrant and Palbociclib in advanced solid tumours, run by Pikavation Therapeutics, Inc., now recruiting.

Overview Connected3

Overview

SNV4818 in Participants With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06736704 by Pikavation Therapeutics, Inc., with 320 participants planned, started 2025-02-20 and due to reach its primary completion in 2027-04. Interventions recorded: SNV4818, Fulvestrant and Palbociclib.

Setting

A Phase 1/2, Open-Label Dose Escalation and Expansion Study of SNV4818 as Monotherapy or in Combination With Other Anticancer Agents in Participants With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Pikavation Therapeutics, Inc.

Registry

Started

2025-02-20

Enrolled

320 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedInjectable SERD

Fulvestrant · Faslodex

ApprovedSmall-molecule CDK4/6 inhibitor

Palbociclib · Ibrance

Evidence strength26/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
320 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06736704

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

Fulvestrant
Palbociclib

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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