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Trials
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

trialsTrialRecruiting

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

A phase 1/2 trial of CRB-601 monoclonal antibody in advanced solid tumours, run by Corbus Pharmaceuticals Inc., now recruiting.

Overview Connected2

Overview

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor. is a phase 1/2 interventional study registered as NCT06603844 by Corbus Pharmaceuticals Inc., with 156 participants planned, started 2024-12-04 and due to reach its primary completion in 2026-11-01. Interventions recorded: CRB-601 monoclonal antibody and Anti-PD-1 monoclonal antibody.

Setting

A Phase 1/2 Study to Investigate the Safety, Pharmacokinetics and Efficacy of CRB-601, a Monoclonal Antibody Against Integrin avb8, in Patients With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Corbus Pharmaceuticals Inc.

Registry

Started

2024-12-04

Enrolled

156 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Corbus Pharmaceuticals

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
156 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06603844

Data

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Cancers

Metastatic cancer (cancer that has spread)

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Corbus Pharmaceuticals

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