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Trials
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

trialsTrialRecruiting

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

A phase 1/2 trial of CRB-701 in advanced solid tumours, run by Corbus Pharmaceuticals Inc., now recruiting.

Overview Connected3

Overview

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors is a phase 1/2 interventional study registered as NCT06265727 by Corbus Pharmaceuticals Inc., with 348 participants planned, started 2024-04-01 and due to reach its primary completion in 2027-01-16. Interventions recorded: CRB-701 and Anti-PD-1.

Setting

A Phase 1/2 Study to Investigate the Safety, Pharmacokinetics, and Efficacy of CRB-701, an Antibody-drug Conjugate Targeting Nectin-4, in Patients With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Corbus Pharmaceuticals Inc.

Registry

Started

2024-04-01

Enrolled

348 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 2ADC

companies

Corbus Pharmaceuticals

Evidence strength21/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
348 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06265727

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

CRB-701

Companies

Corbus Pharmaceuticals

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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