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Trials
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

trialsTrialRecruiting

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

A phase 1/2 trial of Patritumab deruxtecan in advanced solid tumours, run by Merck Sharp & Dohme LLC, now recruiting.

Also called: HERTHENA-PanTumor02

Overview Connected5

Overview

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02) is a phase 1/2 interventional study registered as NCT06596694 by Merck Sharp & Dohme LLC, with 180 participants planned, started 2024-11-03 and due to reach its primary completion in 2028-12-07. Interventions recorded: Patritumab deruxtecan.

Setting

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Gastrointestinal Cancers

Phase

Phase 1/2

Sponsor

Merck Sharp & Dohme LLC

Registry

Started

2024-11-03

Enrolled

180 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Antibody-drug conjugate (ADC)

drugs

Phase 3ADC

Patritumab deruxtecan

companies

Daiichi Sankyo Merck & Co. (MSD)

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
180 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT06596694

Data

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

Antibody-drug conjugate (ADC)

Products

Patritumab deruxtecan

Companies

Merck & Co. (MSD)
Daiichi Sankyo

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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