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Trials
A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

trialsTrialActive

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

A phase 1/2 trial of APL-5125 in colorectal cancer, biliary tract cancer, appendiceal cancer and pseudomyxoma peritonei, pancreatic ductal adenocarcinoma, gastric & gastro-oesophageal junction cancer and endometrial cancer, run by Apollo Therapeutics Ltd, active and no longer recruiting.

Overview Connected6

Overview

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06399757 by Apollo Therapeutics Ltd, with 100 participants enrolled, started 2024-06-18 and due to reach its primary completion in 2027-04. Interventions recorded: APL-5125.

Setting

A Phase 1/2 Study to Assess the Safety and Antitumor Activity of APL-5125 in Adults With Selected Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Apollo Therapeutics Ltd

Registry

Started

2024-06-18

Enrolled

100 enrolled

Connected

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cancers

Appendiceal cancer and pseudomyxoma peritonei Biliary tract cancer (cholangiocarcinoma)Colorectal cancer Endometrial cancer Gastric & gastro-oesophageal junction cancer Pancreatic ductal adenocarcinoma

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
100 enrolled+10
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06399757

Data

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Cancers

Colorectal cancer
Biliary tract cancer (cholangiocarcinoma)
Appendiceal cancer and pseudomyxoma peritonei
Pancreatic ductal adenocarcinoma
Gastric & gastro-oesophageal junction cancer
Endometrial cancer

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