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Trials
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

trialsTrialRecruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

A phase 1/2 trial of ETX-19477 in ovarian cancer, prostate cancer, endometrial cancer, colorectal cancer and gastric & gastro-oesophageal junction cancer, run by 858 Therapeutics, Inc., now recruiting.

Also called: ERADIC8

Overview Connected5

Overview

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies is a phase 1/2 interventional study registered as NCT06395519 by 858 Therapeutics, Inc., with 120 participants planned, started 2024-05-13 and due to reach its primary completion in 2026-12. Interventions recorded: ETX-19477.

Setting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

Phase

Phase 1/2

Sponsor

858 Therapeutics, Inc.

Registry

Started

2024-05-13

Enrolled

120 enrolled

Connected

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cancers

Colorectal cancer Endometrial cancer Gastric & gastro-oesophageal junction cancer Ovarian cancer Prostate cancer

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
120 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Add 115 registry trial acronyms from the CT.gov acronym f… · diff · file

Sources & links

ClinicalTrials.gov NCT06395519

Data

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Cancers

Ovarian cancer
Prostate cancer
Endometrial cancer
Colorectal cancer
Gastric & gastro-oesophageal junction cancer

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