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Trials
TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies

trialsTrialRecruiting

TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies

A phase 1/2 trial of TGRX-814 in non-Hodgkin lymphoma, acute myeloid leukaemia, acute lymphoblastic leukaemia and myelodysplastic syndromes / neoplasms, run by Shenzhen TargetRx Co., Ltd., now recruiting.

Overview Connected5

Overview

TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies is a phase 1/2 interventional study registered as NCT06206174 by Shenzhen TargetRx Co., Ltd., with 30 participants planned, started 2024-03-06 and due to reach its primary completion in 2025-02-28. Interventions recorded: TGRX-814.

Setting

A Single-arm, Open-label, Dose Escalation and Expansion Phase I/II Study Evaluating Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TGRX-814 Monotherapy and Combination Therapy in Patients With Hematological Malignancies

Phase

Phase 1/2

Sponsor

Shenzhen TargetRx Co., Ltd.

Registry

Started

2024-03-06

Enrolled

30 enrolled

Connected

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cancers

Acute lymphoblastic leukaemia Acute myeloid leukaemia Myelodysplastic syndromes / neoplasms (MDS)Non-Hodgkin lymphoma (all types)

companies

Shenzhen TargetRx

Evidence strength15/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
30 enrolled+7
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06206174

Data

JSON ·

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Cancers

Non-Hodgkin lymphoma (all types)
Acute myeloid leukaemia
Acute lymphoblastic leukaemia
Myelodysplastic syndromes / neoplasms (MDS)

Companies

Shenzhen TargetRx

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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