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Trials
AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

trialsTrialRecruiting

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

A phase 1/2 trial of AZD0120 in multiple myeloma, run by AstraZeneca, now recruiting.

Also called: DURGA-1

Overview Connected4

Overview

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1) is a phase 1/2 interventional study registered as NCT05850234 by AstraZeneca, with 232 participants planned, started 2023-07-20 and due to reach its primary completion in 2027-10-01. Interventions recorded: AZD0120.

Setting

A Phase Ib/II Study of AZD0120, Dual-Targeting Autologous Chimeric Antigen Receptor T-cell (CAR T) Therapy Directed Against CD19 and B-cell Maturation Antigen (BCMA) in Participants With Relapsed/Refractory Multiple Myeloma (DURGA-1)

Phase

Phase 1/2

Sponsor

AstraZeneca

Registry

Started

2023-07-20

Enrolled

232 enrolled

Connected

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cancers

Multiple myeloma Relapsed or refractory multiple myeloma

drugs

Phase 3CAR-T cell therapy

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
232 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT05850234

Data

JSON ·

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How review works

Cancers

Multiple myeloma
Relapsed or refractory multiple myeloma

Products

AZD0120

Companies

AstraZeneca

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct05850234.

WebMCP tools registered on this page: onco_search, onco_get_entity.