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Trials
A Study of TNB-383B in Participants With Relapsed or Refractory Multiple Myeloma

trialsTrialActive

A Study of TNB-383B in Participants With Relapsed or Refractory Multiple Myeloma

A phase 1/2 trial of TNB-383B in multiple myeloma, run by AbbVie, active and no longer recruiting.

Overview Connected3

Overview

A Study of TNB-383B in Participants With Relapsed or Refractory Multiple Myeloma is a phase 1/2 interventional study registered as NCT03933735 by AbbVie, with 220 participants enrolled, started 2019-06-24 and due to reach its primary completion in 2026-05. Interventions recorded: TNB-383B.

Setting

A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of TNB-383B, a Bispecific Antibody Targeting BCMA in Subjects With Relapsed or Refractory Multiple Myeloma

Phase

Phase 1/2

Sponsor

AbbVie

Registry

Started

2019-06-24

Enrolled

220 enrolled

Connected

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cancers

Multiple myeloma Relapsed or refractory multiple myeloma

companies

AbbVie (incl. ImmunoGen, Capstan)

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
220 enrolled+12
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT03933735

Data

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Cancers

Multiple myeloma
Relapsed or refractory multiple myeloma

Companies

AbbVie (incl. ImmunoGen, Capstan)

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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