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Trials
IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer

trialsTrialRecruiting

IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer

A phase 1/2 trial of IN10018 and Gemcitabine in pancreatic ductal adenocarcinoma, run by InxMed (Shanghai) Co., Ltd., now recruiting.

Overview Connected5

Overview

IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer is a phase 1/2 interventional study registered as NCT05827796 by InxMed (Shanghai) Co., Ltd., with 70 participants planned, started 2022-12-08 and due to reach its primary completion in 2025-12-31. Interventions recorded: IN10018, Albumin-Bound Paclitaxel, Gemcitabine and KN046.

Setting

A Phase Ib/II, Open-label Clinical Study to Evaluate the Safety, Tolerability and Antitumor Activities of IN10018+Standard Chemotherapy and IN10018+Standard Chemotherapy+KN046 in Subjects With Advanced Pancreatic Cancer

Phase

Phase 1/2

Sponsor

InxMed (Shanghai) Co., Ltd.

Registry

Started

2022-12-08

Enrolled

70 enrolled

Connected

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cancers

Metastatic pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma

drugs

ApprovedNucleoside analogue (deoxycytidine)

Gemcitabine · Gemzar / Infugem

Phase 3small molecule

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
70 enrolled+9
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Merge five duplicate records · diff · file

Sources & links

ClinicalTrials.gov NCT05827796

Data

JSON ·

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Cancers

Pancreatic ductal adenocarcinoma
Metastatic pancreatic ductal adenocarcinoma

Products

IN10018
Gemcitabine

Companies

InxMed

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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