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Trials
CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular Carcinoma

trialsTrialRecruiting

CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular Carcinoma

A phase 2 trial of Nivolumab in hepatocellular carcinoma and metastatic cancer, run by TaiRx, Inc., now recruiting.

Overview Connected6

Overview

CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular Carcinoma is a phase 2 interventional study registered as NCT05257590 by TaiRx, Inc., with 95 participants planned, started 2022-05-23 and due to reach its primary completion in 2026-12-31. Interventions recorded: Nivolumab Injection [Opdivo], CVM-1118. Conditions listed: Hepatocellular Carcinoma, Advanced Cancer. No results are recorded here; the registry entry is the source.

Setting

A Phase 2, Open-Label Study of CVM-1118 in Combination With Nivolumab in Subjects With Unresectable Advanced Hepatocellular Carcinoma

Phase

Phase 2

Sponsor

TaiRx, Inc.

Registry

Started

2022-05-23

Enrolled

95 enrolled

Connected

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cancers

Advanced hepatocellular carcinoma (BCLC C)Hepatocellular carcinoma Metastatic cancer (cancer that has spread)

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Nivolumab · Opdivo / Opdivo Qvantig (SC)

companies

Evidence strength30/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
95 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT05257590

Data

JSON ·

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Cancers

Hepatocellular carcinoma
Metastatic cancer (cancer that has spread)
Advanced hepatocellular carcinoma (BCLC C)

Technologies

Immune checkpoint inhibitors

Products

Nivolumab

Companies

TaiRx

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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