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Trials
AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

trialsTrialRecruiting

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

A phase 1/2 trial of Venetoclax in acute myeloid leukaemia, run by AB Science, now recruiting.

Overview Connected5

Overview

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia is a phase 1/2 interventional study registered as NCT05211570 by AB Science, with 78 participants planned, started 2022-06-01 and due to reach its primary completion in 2026-08. Interventions recorded: AB8939 and Venetoclax.

Setting

A Phase 1/2 Study to Assess the Safety, Pharmacokinetics, and Efficacy of Daily Intravenous AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Phase

Phase 1/2

Sponsor

AB Science

Registry

Started

2022-06-01

Enrolled

78 enrolled

Connected

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cancers

Acute myeloid leukaemia

technologies

BCL-2 inhibitors Small-molecule kinase inhibitors

drugs

ApprovedSmall-molecule BCL-2 inhibitor

Venetoclax · Venclexta

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
78 enrolled+9
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT05211570

Data

JSON ·

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Cancers

Acute myeloid leukaemia

Technologies

BCL-2 inhibitors
Small-molecule kinase inhibitors

Products

Venetoclax

Companies

AB Science

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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