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Trials
A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

trialsTrialActive

A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

A phase 2 trial of Venetoclax in chronic lymphocytic leukaemia, run by AbbVie, active and no longer recruiting.

Overview Connected6

Overview

A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma is a phase 2 interventional study registered as NCT02966756 by AbbVie, with 66 participants enrolled, started 2017-10-12 and due to reach its primary completion in 2030-12. Interventions recorded: Venetoclax.

Setting

A Phase 2 Open-Label Study of the Efficacy of Venetoclax in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Phase

Phase 2

Sponsor

AbbVie

Registry

Started

2017-10-12

Enrolled

66 enrolled

Connected

Similar pages

Trial
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
Shares BCL-2 inhibitors, AbbVie (incl. ImmunoGen, Capstan), Venetoclax, Chronic lymphocytic leukaemia and the tag pipeline.
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Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab
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A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Shares BCL-2 inhibitors, AbbVie (incl. ImmunoGen, Capstan), Venetoclax, Chronic lymphocytic leukaemia and the tag pipeline.
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Shares BCL-2 inhibitors, Venetoclax, Chronic lymphocytic leukaemia, Small-molecule kinase inhibitors and the tag pipeline.
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Shares BCL-2 inhibitors, Relapsed or refractory chronic lymphocytic leukaemia, Chronic lymphocytic leukaemia, Small-molecule kinase inhibitors and the tag pipeline.

cancers

Chronic lymphocytic leukaemia Relapsed or refractory chronic lymphocytic leukaemia

technologies

BCL-2 inhibitors Small-molecule kinase inhibitors

drugs

ApprovedSmall-molecule BCL-2 inhibitor

Venetoclax · Venclexta

companies

AbbVie (incl. ImmunoGen, Capstan)

Evidence strength29/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
66 enrolled+9
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT02966756

Data

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Cancers

Chronic lymphocytic leukaemia
Relapsed or refractory chronic lymphocytic leukaemia

Technologies

BCL-2 inhibitors
Small-molecule kinase inhibitors

Products

Venetoclax

Companies

AbbVie (incl. ImmunoGen, Capstan)

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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