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Trials
THIO Sequenced With Cemiplimab in Advanced NSCLC

trialsTrialActive

THIO Sequenced With Cemiplimab in Advanced NSCLC

A phase 2 trial of Cemiplimab in non-small-cell lung cancer, run by Maia Biotechnology, active and no longer recruiting.

Overview Connected4

Overview

THIO Sequenced With Cemiplimab in Advanced NSCLC is a phase 2 interventional study registered as NCT05208944 by Maia Biotechnology, with 227 participants enrolled, started 2022-06-08 and due to reach its primary completion in 2027-09-30. Interventions recorded: 6-Thio-2'-Deoxyguanosine and Cemiplimab.

Setting

A Multicenter, Open-Label, Dose-Finding, Phase 2 Study Evaluating THIO Sequenced With Cemiplimab (LIBTAYO®) in Subjects With Advanced Non-Small Cell Lung Cancer (NSCLC)

Phase

Phase 2

Sponsor

Maia Biotechnology

Registry

Started

2022-06-08

Enrolled

227 enrolled

Connected

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cancers

Non-small-cell lung cancer

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Cemiplimab · Libtayo

companies

Maia Biotechnology

Evidence strength32/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
227 enrolled+12
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT05208944

Data

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Cancers

Non-small-cell lung cancer

Technologies

Immune checkpoint inhibitors

Products

Cemiplimab

Companies

Maia Biotechnology

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