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Trials
Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma

trialsTrialActive

Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma

A phase 1/2 trial of Temozolomide in glioma & glioblastoma, run by Nerviano Medical Sciences, active and no longer recruiting.

Overview Connected4

Overview

Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma is a phase 1/2 interventional study registered as NCT04910022 by Nerviano Medical Sciences, with 150 participants enrolled, started 2021-12-01 and due to reach its primary completion in 2027-05-30. Interventions recorded: NMS-03305293 and Temozolomide.

Setting

A Phase I/II Combination Study of NMS-03305293 and Temozolomide in Adult Patients With Recurrent Glioblastoma

Phase

Phase 1/2

Sponsor

Nerviano Medical Sciences

Registry

Started

2021-12-01

Enrolled

150 enrolled

Connected

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cancers

Glioma & glioblastoma

technologies

Cytotoxic chemotherapy

drugs

ApprovedOral alkylating chemotherapy

Temozolomide · Temodar

companies

Nerviano Medical Sciences

Evidence strength24/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
150 enrolled+11
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 5 sponsor companies · diff · file

Sources & links

ClinicalTrials.gov NCT04910022

Data

JSON ·

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Cancers

Glioma & glioblastoma

Technologies

Cytotoxic chemotherapy

Products

Temozolomide

Companies

Nerviano Medical Sciences

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

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