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Trials
A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

trialsTrialActive

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

A phase 2 trial of Berubicin in glioma & glioblastoma, run by CNS Pharmaceuticals, Inc., active and no longer recruiting.

Overview Connected3

Overview

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme is a phase 2 interventional study registered as NCT04762069 by CNS Pharmaceuticals, Inc., with 252 participants enrolled, started 2021-05-18 and due to reach its primary completion in 2026-04-27. Interventions recorded: Berubicin and Lomustine.

Setting

A Multicenter, Open-Label Study With a Randomized Control Arm of the Efficacy, Safety, and Pharmacokinetics of Intravenously Infused Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme After Failure of Standard First Line Therapy

Phase

Phase 2

Sponsor

CNS Pharmaceuticals, Inc.

Registry

Started

2021-05-18

Enrolled

252 enrolled

Connected

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cancers

Glioma & glioblastoma

technologies

Cytotoxic chemotherapy

drugs

ApprovedOral nitrosourea chemotherapy

Lomustine (CCNU) · Gleostine

Evidence strength32/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
252 enrolled+12
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT04762069

Data

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Cancers

Glioma & glioblastoma

Technologies

Cytotoxic chemotherapy

Products

Lomustine (CCNU)

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