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A phase 3 trial of Palifermin in Multiple myeloma, run by Swedish Orphan Biovitrum, completed.
A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Multiple Myeloma is a phase 3 interventional study registered as NCT00434161 by Swedish Orphan Biovitrum, with 281 participants recorded, started 2006-12 and reaching its primary completion in 2009-03. Interventions recorded: Palifermin before only, Placebo, Palifermin before and after. Conditions recorded: Multiple Myeloma.
Linked to the drug Palifermin because the registry names it among its interventions and Multiple myeloma among its conditions. Registry record only: no result has been read by an editor.
Numbers are from the trial as recorded here; see the source links in the table below. This is orientation, not medical advice: ask your team how closely the trial population matches you.
281 enrolled.
Figures from the ClinicalTrials.gov results section (first posted 2015-03-10), not from a publication
SourceIQR 35.9 to NA; Figures from the ClinicalTrials.gov results section (first posted 2015-03-10), not from a publication · Median and quartile 3 values are not available because a small number of participants died.
SourceIQR 8.4 to 24.0; Figures from the ClinicalTrials.gov results section (first posted 2015-03-10), not from a publication · IQR 11.9 to 27.5
Source| Endpoint | Arm | n | Value | HR (95% CI) | p | Source |
|---|---|---|---|---|---|---|
| Incidence of Cataract Development or Progression at Month 12., Yesprimary | Placebo | 22 | 4 participants | - | - | link |
| Palifermin | 79 | 25 participants | ||||
| Overall Survival | Palifermin (Palifermin Before Only and, Before and After) | 220 | 50.6 months | 0.64 (0.33 to 1.26) | 0.192 | link |
| Placebo | 57 | Median and quartile 3 values are not available because a small number of participants died. | ||||
| Progression Free Survival | Palifermin (Palifermin Before Only and, Before and After) | 220 | 15.1 months | 0.8 (0.55 to 1.16) | 0.236 | link |
| Placebo | 57 | 18.3 months |
Shares Palifermin, Sobi (Swedish Orphan Biovitrum) and the tag pipeline.
Shares Palifermin, Sobi (Swedish Orphan Biovitrum) and the tag pipeline.
Shares Sobi (Swedish Orphan Biovitrum) and the tag pipeline.
Shares Multiple myeloma and the tag pipeline.
Shares Multiple myeloma and the tag pipeline.
Shares Multiple myeloma and the tag pipeline.
Shares Multiple myeloma and the tag pipeline.
Shares Multiple myeloma and the tag pipeline.