The healthy organs near a tumour that limit how much dose can be given, each with a maximum dose or dose-volume limit the plan must respect (for example, keeping the spinal cord below about 45 to 50 Gy).
Every plan trades tumour dose against the tolerance of nearby organs: spinal cord, brainstem, optic nerves, lungs, heart, kidneys, rectum and bladder among them. Dose constraints come from decades of outcome data, summarised in the QUANTEC reviews and, for stereotactic treatment, HyTEC, and are expressed as maximum point doses or the volume allowed above a threshold. Meeting the constraints is what the optimiser and the planner negotiate.
Showing the technology this term belongs to: IMRT / IGRT (modern external beam).
Shares Volumetric modulated arc therapy (VMAT), Adaptive radiotherapy (online replanning), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares Adaptive radiotherapy (online replanning), Radiotherapy treatment planning and QA software and the tag radiation-wave1.
Shares Adaptive radiotherapy (online replanning), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares C-arm medical linear accelerators (TrueBeam, Versa HD and others), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares Tumour control and normal tissue complication probability (TCP and NTCP) and the tag radiation-wave1.
Shares Tumour control and normal tissue complication probability (TCP and NTCP), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares Radiotherapy treatment planning and QA software, IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares C-arm medical linear accelerators (TrueBeam, Versa HD and others), IMRT / IGRT (modern external beam) and the tag radiation-wave1.