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Removing the uterus (womb), often with the cervix, tubes and ovaries. Simple hysterectomy is the standard curative operation for endometrial cancer, and radical hysterectomy, which also removes tissue beside the cervix and the upper vagina, treats early cervical cancer; the LACC trial showed open surgery beats laparoscopic for cervical cancer.
Simple hysterectomy with bilateral salpingo-oophorectomy and sentinel node mapping is the standard for endometrial cancer, where minimally invasive surgery is safe (LAP2, LACE). For cervical cancer, radical hysterectomy removes parametrial tissue and upper vagina; the LACC trial (2018) showed open surgery gave better survival than laparoscopic, reversing practice, while SHAPE showed simple hysterectomy suffices for small low-risk tumours. Fertility-sparing trachelectomy is an option for young women with small cervical tumours.
Shares POLE-ultramutated endometrial cancer, p53-abnormal endometrial cancer, including uterine serous carcinoma, Endometrial cancer with no specific molecular profile, Mismatch-repair-deficient endometrial cancer.
Shares POLE-ultramutated endometrial cancer, Uterine carcinosarcoma, p53-abnormal endometrial cancer, including uterine serous carcinoma, Endometrial cancer with no specific molecular profile.
Shares POLE-ultramutated endometrial cancer, p53-abnormal endometrial cancer, including uterine serous carcinoma, Mismatch-repair-deficient endometrial cancer.
Shares Uterine carcinosarcoma, p53-abnormal endometrial cancer, including uterine serous carcinoma, Endometrial cancer with no specific molecular profile, Mismatch-repair-deficient endometrial cancer.
Shares POLE-ultramutated endometrial cancer, p53-abnormal endometrial cancer, including uterine serous carcinoma, Endometrial cancer with no specific molecular profile, Mismatch-repair-deficient endometrial cancer.
Shares POLE-ultramutated endometrial cancer, Endometrial cancer with no specific molecular profile, Endometrial cancer.
Shares POLE-ultramutated endometrial cancer, Endometrial cancer with no specific molecular profile, Endometrial cancer.
Shares POLE-ultramutated endometrial cancer, p53-abnormal endometrial cancer, including uterine serous carcinoma.