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Removing the bladder (and nearby organs) for bladder cancer that has grown into the muscle wall; urine is then diverted through a stoma or a new bladder made of bowel.
The standard for muscle-invasive bladder cancer (MIBC), preceded by cisplatin-based neoadjuvant chemotherapy or, since NIAGARA, chemo-immunotherapy. Reconstruction uses an ileal conduit (external bag) or an orthotopic neobladder. It is a major operation with 60% complication rates and a permanent change to daily life, so bladder-sparing trimodality therapy (TURBT plus chemoradiation) and, for patients with complete response to enfortumab vedotin plus pembrolizumab, bladder preservation trials are active alternatives.
Shares Non-muscle-invasive bladder cancer, Bladder & urothelial cancer.
Shares Non-muscle-invasive bladder cancer, Bladder & urothelial cancer.
Shares Non-muscle-invasive bladder cancer, Bladder & urothelial cancer.
Shares Non-muscle-invasive bladder cancer, Bladder & urothelial cancer.
Shares Non-muscle-invasive vs muscle-invasive bladder cancer (NMIBC / MIBC), Bladder & urothelial cancer.
Shares Non-muscle-invasive bladder cancer, Bladder & urothelial cancer.
Shares Muscle-invasive and advanced bladder cancer, Bladder & urothelial cancer.
Shares Muscle-invasive and advanced bladder cancer, Bladder & urothelial cancer.