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Removing the fallopian tubes, where most ovarian cancer starts, during other pelvic surgery or in women at inherited risk.
Because high-grade serous cancer originates in the tubal fimbria, removing the tubes at hysterectomy or instead of tubal ligation (opportunistic salpingectomy) is recommended by ACOG and SGO for average-risk women. In BRCA carriers, salpingo-oophorectomy by age 35-45 remains standard; salpingectomy with delayed oophorectomy (TUBA-WISP II, SOROCk) is under study to postpone surgical menopause. Population data from British Columbia show falling incidence after policy adoption.
Removing the fallopian tubes eliminates the tissue of origin of high-grade serous carcinoma while sparing ovarian hormone production.
Query for this technology: (TITLE:"Risk-reducing and opportunistic salpingectomy" OR ABSTRACT:"Risk-reducing and opportunistic salpingectomy") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Risk-reducing and opportunistic salpingectomy, not a curated reading list.
Shares High-grade serous ovarian carcinoma (HGSOC), Hereditary cancer syndromes, Inherited risk is mostly unidentified, Ovarian cancer.
Shares Angelina Jolie, Hereditary cancer syndromes, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).
Shares Chemoprevention & risk-reducing surgery, Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).
Shares Chemoprevention & risk-reducing surgery, Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).
Shares Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).
Shares Angelina Jolie, Chemoprevention & risk-reducing surgery, BRCA1 / BRCA2 (HRD), Ovarian cancer.
Shares Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).
Shares Chemoprevention & risk-reducing surgery, Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).