UGT1A (UDP glucuronosyltransferase family 1 member A complex locus) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer.
UniProt has no function text for this gene; HGNC names it "UDP glucuronosyltransferase family 1 member A complex locus".
CIViC holds 1 clinical evidence item and 0 assertions across 2 variants, naming Ganetespib.
In plain words · UGT1A (UDP glucuronosyltransferase family 1 member A complex locus) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer.
UGT1A (UDP glucuronosyltransferase family 1 member A complex locus) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer.
UniProt has no function text for this gene; HGNC names it "UDP glucuronosyltransferase family 1 member A complex locus". Locus 2q37 (HGNC).
No product in this corpus aims at UGT1A yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
Specificity not established: the Human Protein Atlas has no row for UGT1A and no corpus medicine is aimed at it. Distribution: 1 cancer family in the corpus carries a prevalence row, label threshold or catalogue link for it (Colorectal cancer). (No rule of scripts/fetch-target-specificity.ts fired.)
Sources: HGNC HGNC:12529; CIViC gene UGT1A
Sources: HGNC HGNC:12529 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); CIViC gene UGT1A (1 evidence items, 0 assertions, 2 variants; diseases: Colorectal Cancer (GraphQL API, CC0))
UniProt has no function text for this gene; HGNC names it "UDP glucuronosyltransferase family 1 member A complex locus". Locus 2q37 (HGNC).
Query for this target: (TITLE:"UGT1A" OR ABSTRACT:"UGT1A" OR TITLE:"UDP glucuronosyltransferase family 1 member A complex locus" OR ABSTRACT:"UDP glucuronosyltransferase family 1 member A complex locus" OR TITLE:"UGT1A@" OR ABSTRACT:"UGT1A@") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about UGT1A, not a curated reading list.