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SKIL (Ski-like protein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
May have regulatory role in cell division or differentiation in response to extracellular signals.
Open Targets scores its association with cancer at 0.52 (direct and indirect evidence; datatypes literature 0.95, animal model 0.37, genetic association 0.62, somatic mutation 0.23).
In plain words · SKIL (Ski-like protein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
SKIL (Ski-like protein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
May have regulatory role in cell division or differentiation in response to extracellular signals. Locus 3q26.2 (HGNC).
No product in this corpus aims at SKIL yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1989. Earliest sequence paper UniProt cites for the protein: Nomura et al, Nucleic Acids Res, 1989, "Isolation of human cDNA clones of ski and the ski-related gene, sno". Source.
Sources: HGNC HGNC:10897 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P12757 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000136603 (association with cancer (MONDO_0004992) 0.52; per-cancer scores at or above 0.5: prostate cancer 0.51 (GraphQL API, CC0))
May have regulatory role in cell division or differentiation in response to extracellular signals. Locus 3q26.2 (HGNC).
Query for this target: (TITLE:"SKIL" OR ABSTRACT:"SKIL" OR TITLE:"SKI like proto-oncogene" OR ABSTRACT:"SKI like proto-oncogene" OR TITLE:"Ski-like protein" OR ABSTRACT:"Ski-like protein" OR TITLE:"SnoN" OR ABSTRACT:"SnoN" OR TITLE:"SnoA" OR ABSTRACT:"SnoA") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SKIL, not a curated reading list.