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NUTM2B (NUT family member 2B) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Sarcomas.
UniProt has no function text for A6NNL0; HGNC names it "NUT family member 2B".
Open Targets scores its association with cancer at 0.61 (direct and indirect evidence; datatypes literature 0.70, genetic association 0.00, somatic mutation 0.97).
In plain words · NUTM2B (NUT family member 2B) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Sarcomas.
NUTM2B (NUT family member 2B) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Sarcomas.
UniProt has no function text for A6NNL0; HGNC names it "NUT family member 2B". Locus 10q22.3 (HGNC).
No product in this corpus aims at NUTM2B yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2004. Earliest sequence paper UniProt cites for the protein: Deloukas et al, Nature, 2004, "The DNA sequence and comparative analysis of human chromosome 10". Source.
Sources: HGNC HGNC:23445 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt A6NNL0 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000188199 (association with cancer (MONDO_0004992) 0.61; per-cancer scores at or above 0.5: sarcoma 0.58 (GraphQL API, CC0))
UniProt has no function text for A6NNL0; HGNC names it "NUT family member 2B". Locus 10q22.3 (HGNC).
Query for this target: (TITLE:"NUTM2B" OR ABSTRACT:"NUTM2B" OR TITLE:"NUT family member 2B" OR ABSTRACT:"NUT family member 2B" OR TITLE:"bA119F19.1" OR ABSTRACT:"bA119F19.1" OR TITLE:"FAM22B" OR ABSTRACT:"FAM22B") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about NUTM2B, not a curated reading list.