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MTCP1 (Protein p13 MTCP-1) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.
Enhances the phosphorylation and activation of AKT1 and AKT2.
Open Targets scores its association with cancer at 0.60 (direct and indirect evidence; datatypes literature 0.53, genetic association 0.00, somatic mutation 0.96).
In plain words · MTCP1 (Protein p13 MTCP-1) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.
MTCP1 (Protein p13 MTCP-1) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.
Enhances the phosphorylation and activation of AKT1 and AKT2. Locus Xq28 (HGNC).
No product in this corpus aims at MTCP1 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1993. Earliest sequence paper UniProt cites for the protein: Stern M.-H. et al, Oncogene, 1993, "MTCP-1: a novel gene on the human chromosome Xq28 translocated to the T cell receptor alpha/delta locus in mature T cell proliferations". Source.
Sources: HGNC HGNC:7423 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P56278 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000214827 (association with cancer (MONDO_0004992) 0.60; per-cancer scores at or above 0.5: breast cancer 0.54 (GraphQL API, CC0))
Enhances the phosphorylation and activation of AKT1 and AKT2. Locus Xq28 (HGNC).
Query for this target: (TITLE:"MTCP1" OR ABSTRACT:"MTCP1" OR TITLE:"mature T cell proliferation 1" OR ABSTRACT:"mature T cell proliferation 1" OR TITLE:"Protein p13 MTCP-1" OR ABSTRACT:"Protein p13 MTCP-1" OR TITLE:"P13MTCP1" OR ABSTRACT:"P13MTCP1" OR TITLE:"p8MTCP1" OR ABSTRACT:"p8MTCP1" OR TITLE:"TCL1C" OR ABSTRACT:"TCL1C") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about MTCP1, not a curated reading list.